As we age, most of us will experience some degree of hair loss. But what if there was a way to reverse it or even prevent it? According to a recent study, anti-aging proteins could help make that possible.
Senescent Cells and Proteins
The authors of this study focused on the so-called senescent cells. This term describes the cells that have reached the advanced stages of aging. Namely, they have become so mature that they are no longer able to divide.
It is normal for the cells in our body to become senescent as we reach an older age. What’s more, scientists believe that these cells contribute to the aging, as well as various age-related diseases.
But what causes human cells to become senescent?
The culprits are two proteins – FOXO4 and p53. When they react with each other, they can speed up the aging of the cell. The researchers wanted to know if there was a way to reverse their effects. And, as their findings show, there may be.
The Promising Effects of Anti-Aging Proteins
By modifying the FOXO4 protein, the authors have developed a new one – FOXO4-DRI. Their goal was simple: target the senescent cells and cause them to self-destruct. They hoped that this would help reverse the signs of aging, including hair loss.
They then administered these anti-aging proteins to aged lab mice for almost 10 months. And within the first 10 days, the mice were able to regrow their hair. Not only that but a few weeks later, they were also able to run much faster than before. So it turns out that these anti-aging proteins could restore hair growth and boost vitality in the old age.
The researchers are getting ready to start testing this new method in humans. If it proves safe and effective, it could serve as the basis for future hair loss drugs. And with so many people affected by hair loss, it would surely have a great commercial potential.